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Ultime news
The prevailing view on multiple sclerosis etiopathogenesis has been challenged by the suggested new entity chronic cerebrospinal venous insufficiency. To test this hypothesis, we studied 21 relapsing-remitting multiple sclerosis cases and 20 healthy controls with phasecontrast magnetic resonance imaging. In addition, in multiple sclerosis cases we performed contrastenhanced magnetic resonance angiography. We found no differences regarding internal jugular venous outflow, aqueductal cerebrospinal fluid flow, or the presence of internal jugular blood reflux. Three of 21 cases had internal jugular vein stenoses. In conclusion, we found no evidence confirming the suggested vascular multiple sclerosis hypothesis.
ANN NEUROL 2010;68:255–259
Pubblichiamo l'aggiornamento che l'AIFA ha apportato al foglio di consenso informato per il Tysabri.
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Tysabri – Modulo di inizio trattamento TYSABRI 300 mg concentrato per soluzione per infusione Natalizumab
Legga questo modulo attentamente prima di iniziare il trattamento con TYSABRI. La preghiamo di seguire i consigli contenuti in questo modulo per assicurarsi che lei sia stato pienamente informato e che abbia compreso i rischi della PML (leucoencefalopatia multifocale progressiva), della sindrome IRIS (sindrome infiammatoria da immunoricostituzione) e di altri importanti eventi avversi associati all’utilizzo di TYSABRI.